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<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　糖尿病足是糖尿病的重要并发症之一，给患者带来了很大的痛苦及沉重的经济负担，其常见临床表现为慢性溃疡，疾病的主要严重结局为截肢甚至死亡。研究显示，糖尿病患者一生中发生糖尿病足溃疡的风险高达25%，而这些患者中截肢的比例占到14%-24%。最近，一项关于糖尿病足溃疡与全因死亡率的分析结果，再次提醒我们“关于糖尿病足的预防，强调再多次也不为过”。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"><img class="rich_pages wxw-img" data-ratio="0.75" src="https://mmbiz.qpic.cn/mmbiz_jpg/If1VdkRjOvt81ow5OtaAlEEF0HrXyOOVWUaNhf7Sy9Cu4U2V6M8XzXKNbo6t05r2sqBxxTegvxlG2X7rMWzQMA/640?wx_fmt=jpeg" data-type="jpeg" data-w="1000" data-imgqrcoded="1" style="margin: 0px; padding: 0px; max-width: 100%; height: auto !important; vertical-align: bottom;"/><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　糖尿病足溃疡令全因死亡率大幅增加<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　1.研究描述<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　本项研究旨在探究糖尿病足溃疡与患者全因死亡率之间的关系，研究人员利用EMBASE、MEDLINE、CINAHL、Psychinfo和Cochrane数据库检索了相关文献，最终共纳入了11项观察性研究，涉及参与者446916名，研究人员利用I^2统计量对文献的异质性进行了检验(0%-50%为无至中度异质性，50%-100%为较大至非常大异质性)。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　2.研究结果<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　446916名参与者中，共计发生84131例死亡事件，其中足溃疡组的全因死亡率是非足溃疡组的2.45倍(RR 2.45，95%CI 1.85-2.85)。全因死亡的粗发生率，足溃疡组为181.5例/1000人年，非足溃疡组为230.8例/1000人年。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　在亚组分析中，并没有观察到平均随访时间的不同(≤3年与>3年)会对研究结果造成实质性影响，RR分别为2.43(95%CI 2.27-2.61)和2.26(95%CI 2.13-2.40)。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"><img class="rich_pages wxw-img" data-galleryid="" data-ratio="0.4204131227217497" data-s="300,640" src="https://mmbiz.qpic.cn/mmbiz_png/If1VdkRjOvt81ow5OtaAlEEF0HrXyOOVDEjNZdf5bsvcpZeIF0fmvTicNNVjD2NhqHThm2sBc3HJDUyAN9vibJzQ/640?wx_fmt=png" data-type="png" data-w="823" style="margin: 0px; padding: 0px; max-width: 100%; vertical-align: bottom; font-size: 17px; text-align: center; height: auto !important;"/><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　分析表明，一旦发生足溃疡，患者的全因死亡风险将增加145%，再次提醒我们对于糖尿病足的关注!那么糖尿病足的危险因素和预防措施都有哪些呢?<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　当心可能导致糖尿病足的危险因素<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　1.整体危险因素：研究表明，经济状况差以及缺乏运动的糖尿病患者发生糖尿病足的风险明显升高;男性患者大截肢和小截肢的风险高于女性(分别是女性的1.39和1.77倍);此外，糖尿病并发症/合并症与糖尿病足发生的关系非常密切。<p style="margin-top: 0px; margin-bottom: 0em; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; white-space: normal; text-align: center;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　2.局部危险因素：局部危险因素主要包括糖尿病周围神经病变(重要危险因素)、糖尿病周围动脉病变、截肢(趾)病史、足底压力异常、下肢静脉功能不全。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　做好糖尿病足的预防<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　对于糖尿病足的预防是重中之重，总体来看分为整体预防和局部预防两个方面。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"><img class="rich_pages wxw-img" data-ratio="0.50625" src="https://mmbiz.qpic.cn/mmbiz_jpg/If1VdkRjOvt81ow5OtaAlEEF0HrXyOOVsh91x75XXFKWFkoU6lRmtLxS4B02wQib44mFAytgWNib0dWiajbCSZEMA/640?wx_fmt=jpeg" data-type="jpeg" data-w="640" style="margin: 0px; padding: 0px; max-width: 100%; height: auto !important; vertical-align: bottom;"/><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　1.整体预防：做好疾病的健康宣教、对于血糖及心血管疾病高危因素的控制、戒烟、适度规律的运动。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　2.局部预防：每天应检查足与鞋袜，并且要做好胼胝与嵌甲的处理、足畸形的矫形处理、Charcot神经骨关节病的处理、下肢静脉功能不全的处理、足真菌感染的处理，以及对于皮肤温度的监控。<p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;"> <p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; min-height: 1em; color: rgb(51, 51, 51); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif; font-size: 17px; text-align: justify; white-space: normal;">　　在此提醒广大患者，对于糖尿病足的关注任何时候都不能放松，疾病预防应从日常生活中的一点一滴做起，而对于伴有足病危险因素的糖尿病患者，建议及早进行糖尿病周围神经病变、血管病变和足病的筛查，这对于改善患者生活质量，树立战胜疾病的信心，降低死亡率有重要意义。